Title: The Relative Effectiveness of CBD Use with the Number of Presenting Symptoms: Pilot study

Authors: Miyachi M, Kuwashima A, Arman S, Merrill R. Affiliations: UCLA orofacial pain and sleep medicine clinic

Aim of Investigation:

To investigate the relationship between the number of symptoms for Cannabidiol (CBD) products use and of its effectiveness.

Methods:
An interview survey was performed with patients who visited the UCLA Orofacial Pain Clinic with orofacial pain symptoms and cannabinoid use. The survey included presenting symptoms of CBD use and the scale indicating degree of effectiveness (from 0 to 10). The questionnaires were administered to 10 patients (1 male and 9 females, mean age 46.8 ± 13.2 years). Subjects were divided into two groups according to the scale of effectiveness: group A (scale 0-5) and group B (scale 6-10).

A chi-squared test was performed to test the null hypothesis that there would be no change in effectiveness (between group A and group B) between patients who take CBD products for one symptom and more than one symptom.

Results:
The null hypothesis was supported. There was not a statistically significant association of effectiveness between patients who take CBD products for one symptom and more than one symptom (p=0.78).

Conclusions:
The present pilot study demonstrated that the relative effectiveness of CBD use was not associated with the number of presenting symptoms. Further studies are needed in order to investigate if the use of CBD products has an impact on medications co-administered for pain management.

Acknowledgements and/or Funding Source: None